Association between IL-1β, IL-8, and IL-10 polymorphisms and risk of acute pancreatitis
نویسندگان
چکیده
منابع مشابه
Study on the association between IL-1β, IL-8 and IL-10 gene polymorphisms and risk of coronary artery disease.
We aimed to evaluate the role of genetic polymorphisms in IL-1β, IL-8 and IL-10 in the risk of coronary artery disease (CAD). We identified 325 patients with CAD and 342 control subjects without CAD between January 2013 and December 2014. Genotyping of IL-1β +3954 C/T, IL-1β -511 C/T, IL-8-251T/A, IL-10-1082A/G and IL-10-819C/T was performed in a 384-well plate format on the Sequenom MassARRAY ...
متن کاملAssociation between IL-1β polymorphisms and gastritis risk
BACKGROUND Helicobacter pylori (H. pylori) infection of the human stomach regularly leads to chronic gastric inflammation. The cytokine gene interleukin (IL)-1β has been implicated in influencing the pathology of inflammation induced by H. pylori infection. Currently, several studies have been carried out to investigate the association of IL-1β-511 (rs16944) and IL-1β-31 (rs1143627) polymorphis...
متن کاملAssociation of IL-10 polymorphisms with acute pancreatitis
Background: Interleukin-10 (IL-10) acts as a vital innate immunity receptors involved in immune response. More and more evidences indicate that polymorphisms of IL-10 gene are associated with acute pancreatitis. The aim of this retrospective study was to investigate the relationship of single nucleotide polymorphisms (SNPs) of IL-10 and the risk of acute pancreatitis (AP). Methods: 3 SNPs of IL...
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Brain insults, including neurotrauma, infection, and perinatal injuries such as hypoxic ischemic encephalopathy, generate inflammation in the brain. These inflammatory cascades induce a wide spectrum of cytokines, which can cause neuron degeneration, have neurotoxic effects on brain tissue, and lead to the development of seizures, even if they are subclinical and occur at birth. Cytokines are s...
متن کاملIL-6, IL-10 and IL-17 Gene Polymorphisms in Iranian Women with Recurrent Miscarriage
Background: Pro-inflammatory and anti-inflammatory cytokines and polymorphisms of their genes have been described to be involved in the pathogenesis of recurrent miscarriage (RM). Objective: To investigate the association between RM and five polymorphisms of cytokine genes, interleukin 10 (IL-10), (-592 A/C, -819 C/T, -1082 A/G), IL-6 (-174 C/G) and IL-17 (-197 G/A) in Iranian women. Method: Po...
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ژورنال
عنوان ژورنال: Genetics and Molecular Research
سال: 2015
ISSN: 1676-5680
DOI: 10.4238/2015.june.18.6